Our Product Portfolio
Our analytical product portfolio includes GPC/SEC instruments, columns and detectors, as well as a comprehensive range of (U)HPLC columns. Additionally, we offer dedicated instruments, pre-packed columns, and media for the purification of biomolecules, catering to needs from laboratory to production scale.
Product Categories
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HPLC & UHPLC Columns - Robust and Reproducible Analysis
TSKgel® columns are designed for researchers seeking the highest level of performance. Since the introduction of the first SEC column in 1971, TSKgel columns became increasingly popular in biotechnology and biopharma. Covering the total range of UHPLC, HPLC and SEC, these columns offer high resolution, excellent reproducibility, and long column life.
TSKgel HIC-ADC Columns
TSKgel hydrophobic interaction chromatography (HIC) columns are widely used for analyzing the drug-to-antibody ratios (DARs) in ADCs (antibody-drug conjugates). The new TSKgel HIC-ADC column line features a novel particle technology with increased uniformity and increased ligand density relative to traditional HIC columns.
Download Product OverviewTSKgel SEC Columns
TSKgel SW size exclusion columns are widely used for aqueous analysis and isolation of proteins, antibodies, enzymes, nucleic acids and other biological macromolecules. TSKgel UP-SW columns for UHPLC-SEC applications improve productivity and resolution.
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Bioprocess Media, Columns, and Instruments Highest purity from lab to production
TOYOPEARL®, Ca++Pure-HATM, and TSKgel® chromatography media are specifically designed to purify biomolecules such as therapeutic peptides, proteins, antibodies, and oligonucleotides at lab, pilot, and commercial scale. A choice of process development tools such as our range of SkillPakTM pre-packed columns facilitates the development of robust and efficient purification methods. The OctaveTM MCC solutions help achieving superior productivity levels and cost reduction via multi-column chromatography.
TOYOPEARL Super A Resin
Downstream processing (DSP) of monoclonal antibodies (mAbs) requires an efficient purification process to achieve high product purity. The most important aspect of mAb purification, the capture step, is usually performed with a Protein A chromatography resin, since this alone can achieve >95% purity. To successfully support biopharmaceutical manufacturing, Protein A resins must offer exceptional performance. The new TOYOPEARL Super A resin provides superior dynamic binding capacities and HCP reduction at mild elution pH conditions.
Download Product OverviewOctave MCC Instruments
Multi-column chromatography (MCC) represents a significant advancement in separation and purification techniques. MCC employs multiple smaller columns in a synchronized, continuous cycle. Each column can be used in a different phase of the purification process, enabling simultaneous loading, washing, elution, and regeneration. This dynamic operation results in resin savings, reduced buffer usage, faster processing, and a significantly smaller equipment footprint than traditional systems. The Octave MCC instruments and SkillPak pre-packed columns are part of a holistic approach to achieve superior productivity levels via multi-column chromatography and cost reduction.
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GPC Instruments and Detectors - Sensitive molecular weight measurement
EcoSEC® GPC/SEC systems are designed for robust polymer analysis. Both the ambient and high temperature GPC systems combine advanced solvent delivery, heating and detection to deliver highest reproducibility. The LenSTM3 Multi-Angle Light Scattering (MALS) and MALS-V dual detectors for macromolecule characterization with UHPLC, HPLC and GPC provide unmatched signal-to-noise at extreme angles and true molecular weight.
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Support & Services
Our expert team of chromatographers is committed to providing prompt services and support:
- Recommend the most suitable instrument, column, or resin for your specific.
- Provide assistance with installation, service, maintenance, method development, and troubleshooting.
- Offer guidance on packing large columns effectively.