INTRODUCING TOYOPEARL® SUPER A RESIN
ENHANCE YOUR mAb PURIFICATION
TOYOPEARL Super A resin is a next-generation Protein A chromatography media offering significantly enhanced binding capacity, robust alkaline stability, and excellent pressure/flow characteristics. TOYOPEARL Super A resin is one of the most efficient and durable Protein A media on the market and offers best-in-class process economics for mAb purification.
Please complete the form below to request a sample of TOYOPEARL Super A resin in one of our convenient SkillPak pre-packed column formats:
- SkillPak Super A 1 mL column, 7 mm ID × 2.5 cm
- SkillPak Super A 5 mL column, 8 mm ID × 10 cm
| Features | Advantages | Benefits | |
|---|---|---|---|
| State-of-the-art operational flexibility | |||
| High binding capacity | > 70 mg mAb / mL resin at 5 min RT | Maximizes antibody capture in each purification cycle | Efficient use of resin, reducing costs and increasing productivity for high titres |
| 70% of the binding capacity acheived within 2 min RT | Faster processing times due to high binding efficiency | ||
| Provides flexibility for Batch and Continuous operations | |||
| High Alkaline Stability | More than 90 % DBC retained after 100 CIP cycles at 0.5 N NaOH | Allows for rigorous cleaning and sanitization protocols | Longer lifespan of the resin, reducing replacement frequency and costs |
| Consistent performance even after repeated exposure to harsh cleaning agents | |||
| Low Pressure Resistance | Up to 800 cm/h flow rates can be achieved with a back pressure of less than 2 bar | Increased throughput, allowing for faster processing of large volumes | Flexibility to operate at higher flow rates |
| Superior critical process performance | |||
| High Elution pH | Enables antibody elution at high pH levels of 5 | Maximizes structural integrity of mAbs and minimizes aggregate formation | Improved recovery of antibodies, maintaining their integrity and activity |
| Low Elution Volume | Elutes antibodies in minimal volumes | Produces highly concentrated antibody solutions | Higher concentration of eluted product, reducing the load on subsequent unit operations |
| Recovery of Highly Pure mAbs | > 95% reduction in HCP | Minimizes impurities in the purified product and reduces the burden on the subsequent Downstream steps | Improves the efficiency of the complete Downstream steps |
Want to learn more?
Download Product Overview
Download Performance Data
View our on-demand BioPharm webinar
Need assistance?
Our product management team is here to support your purification challenges in biomanufacturing.
| In EMEA | In the Americas |
| Patrick Endres Manager Product Management info.tbg@tosoh.com | Phu Duong Sr. Manager Product Management info.tbl@tosoh.com |